Principais desfechos fatais em indivíduos cardiopatas acometidos por COVID-19

Patricia Veiga Nascimento, Monneglesia Santana Lopes Cardoso, Ana Carolina Conceição Neves

Resumo


Objetivo: identificar os principais desfechos fatais em indivíduos cardiopatas acometidos por COVID-19. Método: Trata-se de um estudo de natureza qualitativa, do tipo revisão integrativa da literatura, por meio dos descritores: Cardiopatias; Evolução Fatal; Infecções por Coronavírus e COVID-19, nas bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Medical Literature Analysis and Retrieval Sistem on-line (Medline); National Institutes of Health's National Library of Medicine (NIH/NLM) – PubMed; PubMed Central. Resultados: Dos 13 estudos incluídos após critérios de exclusão, somente oito textos na íntegra contemplaram elementos que respondiam à pergunta da pesquisa. Os mecanismos pelo quais o SARS-CoV-2 promovem lesões ao tecido miocárdico ainda não são completamente conhecidos. No entanto, acredita-se que há um risco aumentado de lesão cardíaca aguda associada à infecção mais grave por COVID-19 e essa lesão está associada ao evento fatal. Conclusão: Os achados desse estudo permitiram identificar os principais desfechos fatais em indivíduos cardiopatas acometidos por COVID-19, ademais demonstram que a atenção e o cuidado aos portadores de cardiopatias após o diagnóstico da COVID-19 precisam ser intensificados, especialmente pelo fato deste grupo de risco ter maior índice de mortalidade.

Descritores: COVID-19; Cardiopatias; Evolução fatal.


MAIN FATAL OUTCOMES IN INDIVIDUALS WITH CARDIOPATHIES STRICKEN BY COVID-19

Objective: To identify the main fatal outcomes of individuals with cardiopathies stricken by COVID-19. Method: A study of a qualitative nature, of a literature integrative review using the descriptors: Heart Diseases; Fatal Outcome; Coronavirus and COVID-19 infections, on the following databases: Latin American and Caribbean Health Sciences Literature (LILACS) and Medical Literature Analysis and Retrieval System on-line (Medline); National Institutes of Health's National Library of Medicine (NIH/NLM) – PubMed; PubMed Central. Results: Out of the 13 studies included after the exclusion criteria, only eight texts fully contemplated elements that answered the question of the research. The mechanism through which SARS-CoV-2 caused lesions to the myocardial tissue are not yet completely known. However, it is believed that there is an increased risk of acute cardiac injury associated to a more acute infection through COVID-19 and such injury is associated to the fatal event. Conclusion: The findings of this study permit the identification of the main fatal outcomes in individuals with cardiopathies stricken by COVID-19, as well as demonstrating that the attention and care to individuals with cardiopathies after the diagnosis of the COVID-19 have to be intensified, mainly due to the fact that there is a higher mortality rate in this risk group.

Descriptors: COVID-19; Heart Diseases; Fatal outcome.


PRINCIPALES RESULTADOS FATALES EN INDIVIDUOS CARDIÓPATAS ACOMETIDOS POR COVID-19

Objetivo: identificar los principales resultados fatales en individuos cardiópatas acometido por COVID-19. Método: Se trata de un estudio de naturaleza cualitativa, del tipo revisión integrativa de la literatura, por medio de los descriptores: Cardiopatías; Resultado Fatal; Infecciones por Coronavirus y COVID-19, en las bases de datos: Literatura Latino-Americana y del Caribe en Ciencias de la Salud (LILACS) y Medical Literature Analysis and Retrieval System on-line (Medline); National Institutes of Health's National Library of Medicine (NIH/NLM) – PubMed; PubMed Central. Resultados: De los 13 estudios incluidos después de los criterios de exclusión, solamente ocho textos en la íntegra contemplaron elementos que respondían a la pregunta de la investigación. Los mecanismos por los cuales el SARS-CoV-2 promovieron lesiones al tejido miocárdico aún no son completamente conocidos. No obstante, se cree que existe un riesgo augmentado de lesión cardíaca aguda asociada a la infección más grave por COVID-19 y esa lesión está asociada al evento fatal. Conclusión: Los hallazgos de esa investigación permitieron identificar los principales resultados fatales en individuos cardiópatas acometidos por COVID-19, además demostraron que la atención y el cuidado a los portadores de cardiopatías después del diagnóstico del COVID-19 necesitan ser intensificados, especialmente por el hecho de ese grupo de riesgo tener mayor índice de mortalidad.

Descriptores: COVID-19; Cardiopatías; Resultado fatal.


Texto completo:

PDF

Referências


Sun Y, Dong Y, Wang L, Xie H, Li B, Chang C et al. Characteristics and prognostic factors of disease severity in patients with COVID-19: The Beijing experience. J Autoimmun. 2020 [cited 2020 Apr 27]; 102473: In press. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7180376/.

Cespedes MS, Souza JCRP. SARS-CoV-2: uma revisão para o clínico. Health Sciences. 2020 [cited 2020 Apr 26]. In press. Available from: https://preprints.scielo.org/index.php/scielo/preprint/view/26/41.

Ministério da Saúde (BR). Painel Coronavírus Brasil [Internet]. 2020 [cited 2020 Apr 26]. Available from: https://covid.saude.gov.br/.

World Health Organization. Coronavirus disease (COVID-2019) situation reports – 101. 2020 [cited 2020 Apr 30]. Available from: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200430-sitrep-101-covid-19.pdf?sfvrsn=2ba4e093_2.

Costa IBSS, Bittar CS, Rizk SI, Araújo Filho AE, Santos KAQ, Machado TIV et al. The Heart and COVID-19: What Cardiologists Need to Know. Arq Bras Cardiol. 2020 [cited 2020 Apr 30]; 114(5):805-816. Available from: http://publicacoes.cardiol.br/portal/abc/portugues/aop/2020/AOP_2020-0279.pdf.

Silva TTM, Dantas RAN, Dantas DV, Lima MSM, Alves LCM, Costa ICS, et al. Pacientes submetidos à angioplastia transluminal coronariana: análise epidemiológica e angiográfica. Rev. Enferm. Foco [Internet]. 2019 [cited 2020 Apr 30]; 10(3):126-133. Available from: http://revista.cofen.gov.br/index.php/enfermagem/article/view/1991/566.

Simão LTSS, Lages LP, Paiva MHP, Ribeiro NLS, Araújo ERM, Leão GM. Perfil dos idosos com doenças crônicas não transmissíveis internados em unidade de terapia intensiva. Rev. Enferm. Foco [Internet]. 2019 [cited 2020 Apr 28];10(1):76-80. Available from: http://revista.cofen.gov.br/index.php/enfermagem/article/view/1329.

Sociedade Brasileira de Cardiologia. SBC Informa - Nota de esclarecimento. Infecção pelo Coronavírus 2019 (COVID-19). 13 de março de 2020 [cited 2020 Apr 28]. Available from: http://www.cardiol.br/sbcinforma/2020/20200313-comunicado-coronavirus.html.

Mendes KDS, Silveira RCCP, Galvão CM. Revisão integrativa: método de pesquisa para a incorporação de evidências na saúde e na enfermagem. Texto contexto - enferm. [Internet]. 2008 [cited 2020 Apr 25]; 17(4):758-764. Available from: http://dx.doi.org/10.1590/S0104-07072008000400018.

Sousa LMM, Vieira CMAM, Severino SSP, Antunes AV. A metodologia de revisão integrativa da literatura em enfermagem. Rev Invest Enferm. 2017 [cited 2020 Apr 25]; 17-26. Available from: https://www.researchgate.net/publication/321319742_Metodologia_de_Revisao_Integrativa_da_Literatura_em_Enfermagem.

Ministério da Saúde (BR). Lei nº 9.610, de 19 de fevereiro de 1998. Altera, atualiza e consolida a legislação sobre direitos autorais e dá outras providências. Diário Oficial da União. Brasília: Ministério da Saúde, 1998 [cited 2020 Apr 25]. Available from: http://www.planalto.gov.br/ccivil_03/leis/l9610.htm#:~:text=LEI%20N%C2%BA%209.610%2C%20DE%2019%20DE%20FEVEREIRO%20DE%201998.&text=Altera%2C%20atualiza%20e%20consolida%20a,autorais%20e%20d%C3%A1%20outras%20provid%C3%AAncias.&text=Art.,os%20que%20lhes%20s%C3%A3o%20conexos.

Tersalvi G, Vicenzi M, Calabretta D, Biasco L, Pedrazzini G, Winterton D. Elevated troponin in patients with Coronavirus Disease 2019 (COVID-19): possible mechanisms. J Card Fail. 2020 [cited 2020 Apr 27]; S1071-9164(20):30357-2. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7166030/#!po=8.33333.

Becker RC. Toward understanding the 2019 Coronavirus and its impact on the heart. J Thromb Thrombolysis. 2020 [cited 2020 Apr 27]; 15:1‐10. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7156795/#__ffn_sectitle.

Guo T, Fan Y, Chen M, Wu X, Zhang L, He T et al. Cardiovascular Implications of Fatal Outcomes of Patients with Coronavirus Disease 2019 (COVID-19). JAMA Cardiol. 2020 [cited 2020 Apr 27]: e201017. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7101506/.

Li JW, Han TW, Woodward M, Anderson CS, Zhou H, Chen YD et al. The impact of 2019 novel coronavirus on heart injury: A systemic review and Meta-analysis. Prog in Cardiovasc Dis. 2020 [cited 2020 Apr 27]: S0033-0620(20):30080-3. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7160645/.

Wang L, He W, Yu X, Hu D, Bao M, Liu H et al. Coronavirus disease 2019 in elderly patients: Characteristics and prognostic factors based on 4-week follow-up. J Infect. 2020 [cited 2020 Apr 27]; 80(6):639-645. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7118526/.

Bansal M. Cardiovascular disease and COVID-19. Diabetes Metab Syndr. 2020 [cited 2020 Apr 27]; 14(3):247‐250. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102662/.

Li B, Yang J, Zhao F, Zhi L, Wang X, Liu L et al. Prevalence and impact of cardiovascular metabolic diseases on COVID-19 in China. Clin Res Cardiol. 2020 [cited 2020 Apr 26]; 109(5):531-538. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087935/#CR20.

Du Y, Tu L, Zhu P, Mu M, Wang R, Yang P et al. Clinical Features of 85 Fatal Cases of COVID-19 from Wuhan: A Retrospective Observational Study. Am J Respir Crit Care Med. 2020 [cited 2020 Apr 28]; 201(11):1372-1379. Available from: https://www.ncbi.nlm.nih.gov/pubmed/32242738.

Guan WJ, Liang WH, Zhao Y, Liang HR, Chen ZS, Li YM et al. Comorbidity and its impact on 1590 patients with Covid-19 in China: A Nationwide Analysis. Eur Respir J. 2020 [cited 2020 Apr 28]; 55(5):2000547. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7098485/#.

Vaduganathan M, Vardeny O, Michel T, McMurray JJV, Pfeffer MA, Solomon SD. Renin-Angiotensin-Aldosterone System Inhibitors in Patients with Covid-19. N Engl J Med. 2020 [cited 2020 Apr 28]; 382(17):1653‐1659. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7121452/.

Vlachakis PK, Tentolouris A, Tousoulis D, Tentolouris N. Current data on the cardiovascular effects of COVID-19. Hellenic J Cardiol. 2020 [cited 2020 Apr 28]; S1109-9666(20):30063-4. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7165281/.

Maisch B. SARS-CoV-2 as potential cause of cardiac inflammation and heart failure. Is it the virus, hyperinflammation, or MODS? Herz. 2020 [cited 2020 Apr 28]: 1-2. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7175831/.

Chen R, Liang W, Jiang M, Guan W, Zhan C, Wang T et al. Risk factors of fatal outcome in hospitalized subjects with coronavirus disease 2019 from a nationwide analysis in China. Chest. 2020 [cited 2020 Apr 28]; S0012-3692(20):30710-8. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7158802/#!po=41.6667.




DOI: https://doi.org/10.21675/2357-707X.2020.v11.n2.ESP.3676

Apontamentos

  • Não há apontamentos.


Direitos autorais 2020 Enfermagem em Foco

Licença Creative Commons
Esta obra está licenciada sob uma licença Creative Commons Atribuição 4.0 Internacional.

Eletrônico ISSN: 2357-707X

Impresso ISSN: 2177-4285

Licença Creative Commons
Este trabalho está licenciado com uma Licença Creative Commons - Atribuição 4.0 Internacional.